Periprosthetic joint infection (PJI) is one of the most challenging complications following joint replacement surgery. The management of PJI involves complex decision-making that requires a multidisciplinary approach, integrating advances in diagnostic techniques, surgical interventions, and antimicrobial therapies. This review provides an in-depth analysis of the current protocols for managing PJI, emphasizing the latest evidence-based strategies for diagnosis, surgical treatment options, antibiotic therapy, and prevention. The review also discusses the emerging trends and future directions in PJI management, aiming to provide healthcare professionals with a comprehensive understanding of the current standards and innovations in this field.
Keywords: Periprosthetic joint infection, Joint replacement, Diagnostic techniques, Surgical treatment, antibiotic therapy, Prevention, Multidisciplinary approach.