- Visibility 285 Views
- Downloads 314 Downloads
- Permissions
- DOI 10.18231/j.jsas.2025.020
-
CrossMark
Acral metastasis in renal cell carcinoma
- Author Details:
-
T K Aravind *
-
Harshdeep Singh
-
Siddharth Yadav
T K Aravind *
Harshdeep Singh
Siddharth Yadav
Renal cell carcinoma (RCC) is one unique urological malignancy with an omnipotent ability of metastasizing to a wide variety of potential sites. Acral metastasis is one such extremely rare event that heralds grave prognostic status of the underlying primary malignancy. We report a 57-year-old gentleman presenting with progressively enlarging swelling on the dorsum of the left hand, evaluation of which lead to the diagnosis of renal cell carcinoma with the seldom reported acral metastasis.
Keywords: Acral, Metastasis, Osseous, Bone, Renal, Carcinoma.
References
- Machado V, San-Julian M. Prognosis and treatment of acrometastases: Observational study of 35 cases treated in a single institution. Rev Esp Cir Ortop Traumatol. 2019;63(1):49-55.
- Çiftdemir M, Ustabaşıoğlu FE, Çölbe SA, Üstün F, Usta U, Çiçin İ. Clinicopathological and prognostic characteristics of acral metastases in patients with malignant disease: A retrospective study. Acta Orthop Traumatol Turc. 2021; 55(1):67-72.
- Mavrogenis AF, Mimidis G, Kokkalis ZT. Acrometastases. Eur J Orthop Surg Traumatol. 2014;24(3):279-83.
- Tani S, Morizaki Y, Uehara K. Bone metastasis of limb segments: Is mesometastasis another poor prognostic factor of cancer patients? Jpn J Clin On-col. 2020;50(6):688-92.
- Kerin R. Metastatic tumors of the hand. A review of the literature. J Bone Joint Surg Am. 1983;65(9):1331-5.
- Afshar A, Farhadnia P, Khalkhali H. Metastases to the hand and wrist: an analysis of 221 cases. J Hand Surg Am. 2014;39:923-
- e17.
- Liu WC, Ho CJ, Lu CK, Wu CC, Fu YC, Chien SH. Acrometastasis to metacarpal bone disclosing an occult lung cancer. Case Reports Plast Surg Hand Surg. 2014;1:23-25.
- Stomeo D, Tulli A, Ziranu A, Perisano C, De Santis V, Maccauro G. Acrometastasis: A literature review. Eur Rev Med Pharmacol Sci. 2015;19(15):2906‑15.
- Jaspreet Kaur RM, Kumar M, Vijay P, Julka GKRK. Capitate metastasis in adenocarcinoma of lung. Case Rep. 2014;22(5):2–4.
- Flynn CJ, Danjoux C, Wongetal J. Two cases of acrometastasis to the hands and review of the literature, Current Oncol- ogy. 200815(5):51–8.
- Umer M, Mohib Y, Atif M, Nazim M. Skeletal metastasis in renal cell carcinoma: A review. Ann Med Surg (Lond). 2018;27:9-16.
- Cesana B, Cochet C, Filhol O. New players in the landscape of renal cell carcinoma bone metastasis and therapeutic opportunities. Int J Cancer. 2025;156(3):475‐87.
- Rau A, Lieb WS, Seifert O, et al. Inhibition of tumor cell growth and cancer stem cell expansion by a bispecific antibody targeting EGFR and HER3. Mol Cancer Ther. 2020;19(7):1474-85.
- Hsu CS, Hentz VR, Yao J. Tumours of the hand. Lancet Oncol. 2007;8(2):157-66.